Dimethyl fumarate (Tecfidera)

Dimethyl fumarate simply known as Tecfidera is a disease modifying drug (DMD) for relapsing remitting MS. and is taken everyday as a pill twice a day once in the morning and once in the evening with food. When you first start Tecfidera you will start on half the dosage for the first week to allow your body to get used to the drug before moving on to the full dosage in the second week.

Side Effects

Common side effects can include

  • flushing and feeling hot
  • gastrointestinal upset (feeling sick, diarrhoea, abdominal pain, vomiting, indigestion)
  • decrease in white blood cells
  • rash
  • increased levels of liver enzymes
  • ketones and protein in urine

Less common side effects can include

  • severe flushing
  • progressive multifocal leukoencephalopathy (PML)
  • decreased white blood cell levels (lymphopenia)
  • liver damage
  • severe allergic reaction

A full list of side effects is included in the manufacturer’s Patient Information Leaflet

What Tecfidera Patients Say