Fingolimod (Gilenya)

Fingolimod simply known as Gilenya is is a disease modifying drug for relapsing remitting MS. it is a tablet that is taken once a day. the first tablet will be taken in hospital or clinic under medical supervision as it can be known to lower your heart rate, heart beat and blood pressure. you will be monitored for 6 hours after taking the tablet. after the first tablet you will be able to continue taking the tablet at home without medical supervision.

Side Effects

Common side effect can include

  • headache
  • back pain
  • diarrhoea
  • cough
  • raised liver enzyme levels
  • infections: herpes virus, fungal, flu
  • changes in heartbeat
  • dizziness, weakness
  • lowering of white blood cells
  • skin rash, itching
  • depression
  • eye pain, blurred vision
  • mild increase in blood pressure
  • basal cell carcinoma

Less common side effect can include

  • pneumonia
  • swelling in the back of the eye (macular oedema)
  • low mood
  • lowering of neutrophils (type of white blood cell)

A full list of side effects is included in the manufacturer’s Patient Information Leaflet

What Gilenya Patients Say

Ann
4 years last month had mri and only a very small new lesion had no side effects so far touch wood I was dx 21 years ago and didn’t take meds until 2011 when my ms turned aggressive, put on pregabalin and amitripyline then on Avonex. I was ok injecting for 6 mths then all of a sudden I just couldn’t press the auto injector it would take me all weekend to press it and after a year I gave up, 3 days to press the button n 4 days of flu left no days to enjoy life! So I went on techfidera as soon as I went on full dose I had hot flushes, they got bad that the flushes started at 10am lasted until 2:30pm and woke me several hours thr the night, I was told they would settle down but after a year of living in front of a fan I gave up. So you can see why I like Gilenya one pill once a day at night and I forget I’m on it, I tell newbies to the drug that the worst thing is the boredom with having to be observed for 6 hrs when you take the first pill other than that you get your life back.

Alison
i been on gilenya since april 2019! I was just diagnosed with MS in February. The medication keep me going and no have so much off days. I mean i have good days then i have bad days too. No worst side effects.

nutshell88
I got diagnosed on 2004 age 17 started interferon 2008 or 07 took it for a year couldn’t tolerate it results on mri got worse changed to betaferron or something like that which i take day yes day no mri got worse again after a year changed to avotex after a year or less got second relapse vertigo 2010 they said i must take tysabri interferon doesnt help i refused
stopped treatments 2011 2019 i started Gilenya
it has dangerous side effects after stopping it as i read
but so far its great no sides effects at all
lil sleepy after i take it
has to be at the same time daily